Sunday 26 September 2010

Bismatrol Chewable Tablets


Pronunciation: BIZ-muth sub-sa-LIS-a-late
Generic Name: Bismuth Subsalicylate
Brand Name: Examples include Bismatrol and Pepto-Bismol


Bismatrol Chewable Tablets are used for:

Treating heartburn, upset stomach, indigestion, nausea, diarrhea, or symptoms associated with eating or drinking too much. It may be used to decrease the number of bowel movements and make the stool firmer. It may also be used to treat other conditions as determined by your doctor.


Bismatrol Chewable Tablets are a salicylate. The way that it works is not fully understood. It is thought to limit secretions in the digestive tract, reduce inflammation in the stomach and intestines, and inhibit the growth of certain bacteria and viruses that can cause intestinal tract diseases.


Do NOT use Bismatrol Chewable Tablets if:


  • you are allergic to any ingredient in Bismatrol Chewable Tablets

  • you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, naproxen, celecoxib)

  • you have bleeding problems (eg, hemophilia), active bleeding ulcer, black or bloody stools, or Von Willebrand disease

  • you are taking another salicylate medicine (eg, aspirin)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Bismatrol Chewable Tablets:


Some medical conditions may interact with Bismatrol Chewable Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have diabetes, gout, arthritis, fever, mucus in the stool, inflammation of the stomach, Kawasaki syndrome, kidney problems, chickenpox, the flu, or joint problems (in children), or if you are dehydrated

  • if you have a history of stroke or a certain type of bulging blood vessel (aneurysm) in the brain

Some MEDICINES MAY INTERACT with Bismatrol Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Insulin, methotrexate, or valproic acid because actions and side effects may be increased by Bismatrol Chewable Tablets

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, lisinopril) or sulfinpyrazone because their effectiveness may be decreased by Bismatrol Chewable Tablets

  • Anticoagulants (eg, warfarin) because the risk of bleeding may be increased by Bismatrol Chewable Tablets

  • Salicylates (eg, aspirin) because the risk of side effects or toxic effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bismatrol Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Bismatrol Chewable Tablets:


Use Bismatrol Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Bismatrol Chewable Tablets may be taken with or without food.

  • Do not take tetracyclines (eg, doxycycline) within 2 hours before or after taking Bismatrol Chewable Tablets.

  • Use Bismatrol Chewable Tablets exactly as directed on the package, unless instructed differently by your doctor.

  • Do not take Bismatrol Chewable Tablets with aspirin.

  • Chew thoroughly before swallowing.

  • Drinking extra fluids while you are taking Bismatrol Chewable Tablets are recommended. Check with your doctor for instructions.

  • If you miss a dose of Bismatrol Chewable Tablets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Bismatrol Chewable Tablets.



Important safety information:


  • If the packaging blister is torn or open, do not use that particular tablet.

  • Do not exceed the recommended dose or take Bismatrol Chewable Tablets for longer than 48 hours without checking with your doctor. If your symptoms do not improve within 48 hours or if they become worse or you develop a fever, check with your doctor.

  • Bismatrol Chewable Tablets may color the tongue or stool gray or black. This is a temporary and harmless effect.

  • Do not give Bismatrol Chewable Tablets to a child or teenager who has chickenpox, the flu, or another viral infection. Use of Bismatrol Chewable Tablets for treating the symptoms of a viral infection may cause a serious illness called Reye syndrome.

  • Use Bismatrol Chewable Tablets with extreme caution in CHILDREN because they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Bismatrol Chewable Tablets during pregnancy. Bismatrol Chewable Tablets are excreted in breast milk. Do not breast-feed while taking Bismatrol Chewable Tablets.


Possible side effects of Bismatrol Chewable Tablets:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Temporary and harmless darkening of the tongue or stool.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; hearing loss; nausea; ringing in the ears; severe constipation; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Bismatrol side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; confusion; dehydration; dizziness; new or worsening nausea; ringing in the ears; seizures; unusual bruising or bleeding; vomiting.


Proper storage of Bismatrol Chewable Tablets:

Store Bismatrol Chewable Tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Keep Bismatrol Chewable Tablets out of the reach of children and away from pets.


General information:


  • If you have any questions about Bismatrol Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.

  • Bismatrol Chewable Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bismatrol Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bismatrol resources


  • Bismatrol Side Effects (in more detail)
  • Bismatrol Use in Pregnancy & Breastfeeding
  • Drug Images
  • Bismatrol Drug Interactions
  • Bismatrol Support Group
  • 0 Reviews for Bismatrol - Add your own review/rating


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  • Manufacturer: NOVARTIS

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METHERGINE (methylergonovine maleate - tablet; oral)



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Has a generic version of Methergine been approved?


Yes. The following products are equivalent to Methergine:


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    Approval date: May 2, 2011

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Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Methergine. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




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  • Methylergonovine Consumer Information (Wolters Kluwer)
  • Methylergonovine Tablets Consumer Information (Wolters Kluwer)
  • Methylergonovine oral and injectable Consumer Information (Cerner Multum)

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