Tcis

Generic Name: fluocinonide (Topical application route)

floo-oh-SIN-oh-nide

Commonly used brand name(s)

In the U.S.

• Lidex


• Lidex-E


• Vanos

In Canada

• Lidemol


• Lidex Mild


• Lidex Regular


• Lyderm


• Tcis


• Tiamol


• Topsyn


• Trisyn

Available Dosage Forms:

• Ointment


• Emollient Cream


• Cream


• Solution


• Gel/Jelly

Therapeutic Class: Corticosteroid, Strong

Pharmacologic Class: Adrenal Glucocorticoid

Uses For Tcis

Fluocinonide topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available only with your doctor's prescription.

Before Using Tcis

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of fluocinonide topical in the pediatric population. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully. For Vanos® cream, safety and efficacy have not been established in children younger than 12 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Vanos® cream in the elderly. However, elderly patients are more likely to have age-related medical problems, which may require caution in patients receiving Vanos® cream.

No information is available on the relationship of age to the effects of fluocinonide topical in geriatric patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Cushing's syndrome (adrenal gland disorder) or


• Diabetes or


• Hyperglycemia (high blood sugar) or


• Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

• Infection of the skin at or near the place of application or


• Large sores, broken skin, or severe skin injury at the place of application—The chance of side effects may be increased.

• Perioral dermatitis (skin problem) or


• Rosacea (skin problem)—Vanos® cream should not be used in patients with these conditions.

Proper Use of fluocinonide

This section provides information on the proper use of a number of products that contain fluocinonide. It may not be specific to Tcis. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

If you are using the Vanos® cream:

• Do not use it on the face, groin, or underarms unless directed to do so by your doctor.


• Do not use it for more than 2 weeks unless your doctor tells you otherwise.

To use:

• Wash your hands with soap and water before and after using this medicine.


• Apply a thin layer of this medicine to the affected area of the skin. Rub it in gently.


• Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.


• If the medicine is applied to the diaper area of an infant, do not use tight-fitting diapers or plastic pants unless directed to do so by your doctor.


• If your doctor ordered an occlusive dressing or airtight covering to be applied over the medicine, make sure you know how to apply it. Occlusive dressings increase the amount of medicine absorbed through your skin, so use them only as directed. If you have any questions about this, check with your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage forms (cream, gel, ointment, or solution):
  
  • For redness, itching, and swelling of the skin:
    
    • Adults—Apply to the affected area of the skin two to four times per day.
    
    
    • Children—Apply to the affected area of the skin two to four times per day.
    
    
  
  


• For topical dosage form (cream):
  
  • For atopic dermatitis:
    
    • Adults and children 12 years of age and older—Apply to the affected area of the skin once a day.
    
    
    • Children younger than 12 years of age—Use is not recommended.
    
    
  
  
  • For psoriasis:
    
    • Adults and children 12 years of age and older—Apply to the affected area of the skin one to two times per day.
    
    
    • Children younger than 12 years of age—Use is not recommended.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Tcis

It is very important that your doctor check the progress of you or your child at regular visits for any unwanted effects that may be caused by this medicine.

If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using this medicine: blurred vision; dizziness or fainting; a fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

Stop using this medicine and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Do not use cosmetics or other skin care products on the treated areas.

Tcis Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

• Blistering, burning, crusting, dryness, or flaking of the skin


• irritation


• itching, scaling, severe redness, soreness, or swelling of the skin


• redness and scaling around the mouth


• thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g. between the fingers)


• thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Fever


• headache


• muscle aches


• sore throat


• stuffy or runny nose


• unusual tiredness or weakness

Incidence not known

• Acne or pimples


• burning and itching of the skin with pinhead-sized red blisters


• burning, itching, and pain in hairy areas, or pus at the root of the hair


• increased hair growth on the forehead, back, arms, and legs


• lightening of normal skin color


• lightening of treated areas of dark skin


• reddish purple lines on the arms, face, legs, trunk, or groin


• softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Tcis side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Tcis resources

• Tcis Side Effects (in more detail)
• Tcis Use in Pregnancy & Breastfeeding
• Tcis Drug Interactions
• Tcis Support Group
• 12 Reviews for Tcis - Add your own review/rating

Compare Tcis with other medications

• Atopic Dermatitis
• Dermatitis
• Psoriasis

Ferrex 150

Generic Name: iron supplement (Oral route, Parenteral route)

Commonly used brand name(s)

In the U.S.

• Beef,Iron & Wine


• Bifera


• Elite Iron


• Femiron


• Feosol


• Fergon


• Ferrex 150


• Hemocyte

In Canada

• Fer-In-Sol


• Palafer


• Pms-Ferrous Sulfate

Available Dosage Forms:

• Tablet, Chewable


• Liquid


• Tablet


• Capsule


• Solution


• Tablet, Enteric Coated


• Tablet, Extended Release


• Suspension


• Syrup


• Capsule, Extended Release


• Elixir


• Capsule, Liquid Filled

Uses For Ferrex 150

Iron is a mineral that the body needs to produce red blood cells. When the body does not get enough iron, it cannot produce the number of normal red blood cells needed to keep you in good health. This condition is called iron deficiency (iron shortage) or iron deficiency anemia.

Although many people in the U.S. get enough iron from their diet, some must take additional amounts to meet their needs. For example, iron is sometimes lost with slow or small amounts of bleeding in the body that you would not be aware of and which can only be detected by your doctor. Your doctor can determine if you have an iron deficiency, what is causing the deficiency, and if an iron supplement is necessary.

Lack of iron may lead to unusual tiredness, shortness of breath, a decrease in physical performance, and learning problems in children and adults, and may increase your chance of getting an infection.

Some conditions may increase your need for iron. These include:

• Bleeding problems


• Burns


• Hemodialysis


• Intestinal diseases


• Stomach problems


• Stomach removal


• Use of medicines to increase your red blood cell count

In addition, infants, especially those receiving breast milk or low-iron formulas, may need additional iron.

Increased need for iron supplements should be determined by your health care professional.

Injectable iron is administered only by or under the supervision of your health care professional. Other forms of iron are available without a prescription; however, your health care professional may have special instructions on the proper use and dose for your condition.

Importance of Diet

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.

Iron is found in the diet in two forms—heme iron, which is well absorbed, and nonheme iron, which is poorly absorbed. The best dietary source of absorbable (heme) iron is lean red meat. Chicken, turkey, and fish are also sources of iron, but they contain less than red meat. Cereals, beans, and some vegetables contain poorly absorbed (nonheme) iron. Foods rich in vitamin C (e.g., citrus fruits and fresh vegetables), eaten with small amounts of heme iron-containing foods, such as meat, may increase the amount of nonheme iron absorbed from cereals, beans, and other vegetables. Some foods (e.g., milk, eggs, spinach, fiber-containing, coffee, tea) may decrease the amount of nonheme iron absorbed from foods. Additional iron may be added to food from cooking in iron pots.

The daily amount of iron needed is defined in several different ways.

• For U.S.—


• Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person's age, sex, and physical condition (e.g., pregnancy).


• Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).

• For Canada—


• Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

Normal daily recommended intakes in milligrams (mg) for iron are generally defined as follows (Note that the RDA and RNI are expressed as an actual amount of iron, which is referred to as “elemental”' iron. The product form [e.g., ferrous fumarate, ferrous gluconate, ferrous sulfate] has a different strength):

Persons	U.S. (mg)	Canada (mg)
Infants birth to 3 years of age	6–10	0.3–6
Children 4 to 6 years of age	10	8
Children 7 to 10 years of age	10	8–10
Adolescent and adult males	10	8–10
Adolescent and adult females	10–15	8–13
Pregnant females	30	17–22
Breast-feeding females	15	8–13

Before Using Ferrex 150

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Problems in children have not been reported with intake of normal daily recommended amounts. Iron supplements, when prescribed by your health care professional, are not expected to cause different side effects in children than they do in adults. However, it is important to follow the directions carefully, since iron overdose in children is especially dangerous.

Studies on sodium ferric gluconate have shown that this supplement is safe to use in children ages 6 to 15 years. The safety of sodium ferric gluconate has not been determined in patients who are younger than 6 years of age.

Geriatric

Problems in older adults have not been reported with intake of normal daily recommended amounts. Elderly people sometimes do not absorb iron as easily as younger adults and may need a larger dose. If you think you need to take an iron supplement, check with your health care professional first. Only your health care professional can decide if you need an iron supplement and how much you should take.

Pregnancy

It is especially important that you are receiving enough vitamins and minerals when you become pregnant and that you continue to receive the right amount of vitamins and minerals throughout your pregnancy. Healthy fetal growth and development depend on a steady supply of nutrients from mother to fetus. During the first 3 months of pregnancy, a proper diet usually provides enough iron. However, during the last 6 months, in order to meet the increased needs of the developing baby, an iron supplement may be recommended by your health care professional.

However, taking large amounts of a dietary supplement in pregnancy may be harmful to the mother and/or fetus and should be avoided.

Breast Feeding

It is especially important that you receive the right amounts of vitamins and minerals so that your baby will also get the vitamins and minerals needed to grow properly. Iron normally is present in breast milk in small amounts. When prescribed by a health care professional, iron preparations are not known to cause problems during breast-feeding. However, nursing mothers are advised to check with their health care professional before taking iron supplements or any other medication. Taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or infant and should be avoided.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these dietary supplements, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using dietary supplements in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Altretamine


• Amygdalin


• Deferoxamine


• Digoxin


• Eltrombopag


• Rilpivirine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of dietary supplements in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol abuse (or history of) or


• Blood transfusions (with high red blood cell iron content) or


• Kidney infection or


• Liver disease or


• Porphyria cutaneous tarda—Higher blood levels of the iron supplement may occur, which may increase the chance of side effects.

• Arthritis (rheumatoid) or


• Asthma or allergies or


• Heart disease—The injected form of iron may make these conditions worse.

• Colitis or other intestinal problems or


• Iron overload conditions (e.g., hemochromatosis, hemosiderosis, hemoglobinopathies) or


• Stomach ulcer—Iron supplements may make these conditions worse.

• Other anemias—Iron supplements may increase iron to toxic levels in anemias not associated with iron deficiency.

Proper Use of iron supplement

This section provides information on the proper use of a number of products that contain iron supplement. It may not be specific to Ferrex 150. Please read with care.

After you start using this dietary supplement, continue to return to your health care professional to see if you are benefiting from the iron. Some blood tests may be necessary for this.

Iron is best absorbed when taken on an empty stomach, with water or fruit juice (adults: full glass or 8 ounces; children: ½ glass or 4 ounces), about 1 hour before or 2 hours after meals. However, to lessen the possibility of stomach upset, iron may be taken with food or immediately after meals.

For safe and effective use of iron supplements:

• Follow your health care professional's instructions if this dietary supplement was prescribed.


• Follow the manufacturer's package directions if you are treating yourself. If you think you still need iron after taking it for 1 or 2 months, check with your health care professional.

Liquid forms of iron supplement tend to stain the teeth. To prevent, reduce, or remove these stains:

• Mix each dose in water, fruit juice, or tomato juice. You may use a drinking tube or straw to help keep the iron supplement from getting on the teeth.


• When doses of liquid iron supplement are to be given by dropper, the dose may be placed well back on the tongue and followed with water or juice.


• Iron stains on teeth can usually be removed by brushing with baking soda (sodium bicarbonate) or medicinal peroxide (hydrogen peroxide 3%).

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage forms (capsules, tablets, oral solution):
  
  • To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes:
    
    • For the U.S.
    
    
    • Adult and teenage males—10 milligrams (mg) per day.
    
    
    • Adult and teenage females—10 to 15 mg per day.
    
    
    • Pregnant females—30 mg per day.
    
    
    • Breast-feeding females—15 mg per day.
    
    
    • Children 7 to 10 years of age—10 mg per day.
    
    
    • Children 4 to 6 years of age—10 mg per day.
    
    
    • Children birth to 3 years of age—6 to 10 mg per day.
    
    
    • For Canada
    
    
    • Adult and teenage males—8 to 10 mg per day.
    
    
    • Adult and teenage females—8 to 13 mg per day.
    
    
    • Pregnant females—17 to 22 mg per day.
    
    
    • Breast-feeding females—8 to 13 mg per day.
    
    
    • Children 7 to 10 years of age—8 to 10 mg per day.
    
    
    • Children 4 to 6 years of age—8 mg per day.
    
    
    • Children birth to 3 years of age—0.3 to 6 mg per day.
    
    
  
  
  • To treat deficiency:
    
    • Adults, teenagers, and children— The dose will be determined by your doctor, based on your condition.
    
    
  
  


• For injection dosage forms:
  
  • Adults, teenagers, and children— The dose will be determined by your doctor, based on your condition.
  
  

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Ferrex 150

When iron is combined with certain foods it may lose much of its value. If you are taking iron, the following foods should be avoided, or only taken in very small amounts, for at least 1 hour before or 2 hours after you take iron:

• Cheese and yogurt


• Eggs


• Milk


• Spinach


• Tea or coffee


• Whole-grain breads and cereals and bran

Do not take iron supplements and antacids or calcium supplements at the same time. It is best to space doses of these 2 products 1 to 2 hours apart, to get the full benefit from each medicine or dietary supplement.

If you are taking iron supplements without a prescription:

• Do not take iron supplements by mouth if you are receiving iron injections. To do so may result in iron poisoning.


• Do not regularly take large amounts of iron for longer than 6 months without checking with your health care professional. People differ in their need for iron, and those with certain medical conditions can gradually become poisoned by taking too much iron over a period of time. Also, unabsorbed iron can mask the presence of blood in the stool, which may delay discovery of a serious condition.

If you have been taking a long-acting or coated iron tablet and your stools have not become black, check with your health care professional. The tablets may not be breaking down properly in your stomach, and you may not be receiving enough iron.

It is important to keep iron preparations out of the reach of children. Keep a 1-ounce bottle of syrup of ipecac available at home to be taken in case of an iron overdose emergency when a doctor, poison control center, or emergency room orders its use.

If you think you or anyone else has taken an overdose of iron medicine:

• Call your doctor, a poison control center, or the nearest hospital emergency room at once. Always keep these phone numbers readily available.


• Follow any instructions given to you. If syrup of ipecac has been ordered and given, do not delay going to the emergency room while waiting for the ipecac syrup to empty the stomach, since it may require 20 to 30 minutes to show results


• Go to the emergency room without delay


• Take the container of iron with you.

Early signs of iron overdose may not appear for up to 60 minutes or more. Do not delay going to the emergency room while waiting for signs to appear.

Ferrex 150 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common - with injection only

• Backache , groin, side, or muscle pain


• chest pain


• chills


• dizziness


• fainting


• fast heartbeat


• fever with increased sweating


• flushing


• headache


• metallic taste


• nausea or vomiting


• numbness, pain, or tingling of hands or feet


• pain or redness at injection site


• redness of skin


• skin rash or hives


• swelling of mouth or throat


• troubled breathing

More common - when taken by mouth only

• Abdominal or stomach pain


• cramping (continuing) or soreness

Less common or rare - with injection only

• Double vision


• general unwell feeling


• weakness without feeling dizzy or faint

Less common or rare - when taken by mouth only

• Chest or throat pain, especially when swallowing


• stools with signs of blood (red or black color)

Early symptoms of iron overdose

Symptoms of iron overdose may not occur for up to 60 minutes or more after the overdose was taken. By this time you should have had emergency room treatment. Do not delay going to emergency room while waiting for signs to appear.

• Diarrhea (may contain blood)


• fever


• nausea


• stomach pain or cramping (sharp)


• vomiting, severe (may contain blood)

Late symptoms of iron overdose

• Bluish-colored lips, fingernails, and palms of hands


• convulsions (seizures)


• pale, clammy skin


• shallow and rapid breathing


• unusual tiredness or weakness


• weak and fast heartbeat

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Constipation


• diarrhea


• leg cramps


• nausea


• vomiting

Less common

Stools commonly become dark green or black when iron preparations are taken by mouth. This is caused by unabsorbed iron and is harmless. However, in rare cases, black stools of a sticky consistency may occur along with other side effects such as red streaks in the stool, cramping, soreness, or sharp pains in the stomach or abdominal area. Check with your health care professional immediately if these side effects appear.

If you have been receiving injections of iron, you may notice a brown discoloration of your skin. This color usually fades within several weeks or months.

• Darkened urine


• heartburn


• stained teeth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Isofludem

Isofludem may be available in the countries listed below.

Ingredient matches for Isofludem

Isoflurane

Isoflurane is reported as an ingredient of Isofludem in the following countries:

• Turkey

International Drug Name Search

Tenuate

Generic Name: diethylpropion (dye eth ill PROE pee on)

Brand Names: Tenuate

What is diethylpropion?

Diethylpropion is an appetite suppressant similar to an amphetamine. Diethylpropion stimulates your central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Diethylpropion is used as together with diet and exercise to treat of obesity.

Diethylpropion may also be used for purposes not listed in this medication guide.

What is the most important information I should know about diethylpropion?

Taking diethylpropion in combination with other diet pills or appetite suppressants can cause serious or life threatening medical problems. Do not use any other diet medications while taking diethylpropion, unless your doctor tells you to. You should not take this medication if you are allergic to diethylpropion or if you have pulmonary hypertension, severe coronary artery disease, glaucoma, overactive thyroid, uncontrolled high blood pressure, a history of drug or alcohol addiction, if you are agitated, or if you are taking any other diet pills. Do not use diethylpropion if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before you take diethylpropion, tell your doctor if you have a heart murmur, heart valve disorder, heart rhythm disorder, epilepsy, or if you have taken other diet pills within the past 12 months.

This medication may cause blurred vision and may impair your thinking or reactions. Diethylpropion may also cause restless feelings that can hide the symptoms of extreme tiredness. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Diethylpropion may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it. Do not stop using diethylpropion suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using diethylpropion.

What should I discuss with my healthcare provider before taking diethylpropion?

Taking diethylpropion in combination with other diet pills or appetite suppressants can cause serious or life threatening medical problems. Do not use any other diet medications while taking diethylpropion, unless your doctor tells you to. You should not take this medication if you are allergic to diethylpropion or similar medicines (stimulants, diet pills, cold or allergy medicines), or if you have:

• 
  

  pulmonary hypertension;

  
  


• 
  

  severe coronary artery disease (hardened arteries);

  
  


• 
  

  glaucoma;

  
  


• 
  

  overactive thyroid;

  
  


• 
  

  severe or uncontrolled high blood pressure;

  
  


• 
  

  a history of drug or alcohol addiction;

  
  


• 
  

  if you are in an agitated state; or

  
  


• 
  

  if you are taking any other appetite suppressants or diet pills.

  
  

Do not use diethylpropion if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

To make sure you can safely take diethylpropion, tell your doctor if you have any of these other conditions:

• 
  

  a heart murmur, heart valve disorder, or heart rhythm disorder;

  
  


• 
  

  epilepsy or other seizure disorder; or

  
  


• 
  

  if you have taken other diet pills within the past 12 months.

  
  

Diethylpropion may be habit forming and should be used only by the person it was prescribed for. Never share diethylpropion with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. FDA pregnancy category B. Diethylpropion is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Diethylpropion can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medicine to a child younger than 16 years old.

How should I take diethylpropion?

Take exactly as prescribed. Never take diethylpropion in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your hunger.

Tell your doctor if you do not lose at least 4 pounds after taking the medication for 4 weeks along with a low calorie diet.

Diethylpropion is usually taken once a day in the midmorning.

Do not crush, chew, or break a controlled release tablet. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Diethylpropion is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is already evening. Wait until the next morning to take your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking diethylpropion?

This medication may cause blurred vision and may impair your thinking or reactions. Diethylpropion may also cause restless feelings that can hide the symptoms of extreme tiredness. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of diethylpropion.

Diethylpropion side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using diethylpropion and call your doctor at once if you have a serious side effect such as:

• 
  

  fast, pounding, or uneven heartbeats;

  
  


• 
  

  chest pain, feeling short of breath (even with mild exertion);

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  swelling in your ankles or feet;

  
  


• 
  

  confusion, hallucinations, unusual thoughts or behavior;

  
  


• 
  

  seizure (convulsions);

  
  


• 
  

  muscle movements you cannot control; or

  
  


• 
  

  sudden numbness or weakness, especially on one side of the body.

  
  

Less serious side effects may include:

• 
  

  nausea, vomiting, diarrhea, upset stomach;

  
  


• 
  

  headache, blurred vision;

  
  


• 
  

  feeling nervous, anxious, or jittery;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  dizziness, drowsiness, tired feeling;

  
  


• 
  

  depressed mood;

  
  


• 
  

  dry mouth, unpleasant taste in your mouth;

  
  


• 
  

  decreased sex drive; or

  
  


• 
  

  mild itching or rash.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect diethylpropion?

Tell your doctor about all other medicines you use, especially:

• 
  

  insulin or oral diabetes medication;

  
  


• 
  

  blood pressure medication; or

  
  


• 
  

  stimulants, cold or allergy medicines, ADHD (attention deficit hyperactivity disorder) medicine such as Adderall or Ritalin.

  
  

This list is not complete and other drugs may interact with diethylpropion. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Tenuate resources

• Tenuate Side Effects (in more detail)
• Tenuate Use in Pregnancy & Breastfeeding
• Drug Images
• Tenuate Drug Interactions
• Tenuate Support Group
• 28 Reviews for Tenuate - Add your own review/rating

• Tenuate Advanced Consumer (Micromedex) - Includes Dosage Information


• Tenuate Consumer Overview


• Tenuate MedFacts Consumer Leaflet (Wolters Kluwer)


• Diethylpropion Prescribing Information (FDA)


• Diethylpropion Hydrochloride Monograph (AHFS DI)


• Tenuate Dospan Controlled-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Tenuate with other medications

• Obesity

Where can I get more information?

• Your pharmacist can provide more information about diethylpropion.

See also: Tenuate side effects (in more detail)

Triaminic

Generic Name: chlorpheniramine and phenylpropanolamine (klor feh NEER a meen and feh nill proe pa NO la meen)

Brand Names: A.R.M. Allergy Relief, Allerest 12 Hour, Chlornade, Condrin, Contac 12 Hour, Decongex-3, Demazin, Dura-Vent/A, Equi-Nade, Genamin, Gencold, Histade, Or-Phen-Ade, Ordrine, Ornade Spansules, Resaid, Rescon Liquid, Rhinolar-EX, Teldrin, Triac, Triaminic, Vanex Forte-R

What is chlorpheniramine and phenylpropanolamine?

Chlorpheniramine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in the body. Chlorpheniramine prevents sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.

Phenylpropanolamine is a decongestant. It constricts (shrinks) blood vessels (veins and arteries). This reduces the blood flow to certain areas and allows nasal passages to open up.

Chlorpheniramine and phenylpropanolamine is used to treat nasal congestion and sinusitis (inflammation of the sinuses) associated with allergies, hay fever, and the common cold.

Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Chlorpheniramine and phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about chlorpheniramine and phenylpropanolamine?

Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Use caution when driving, operating machinery, or performing other hazardous activities. Chlorpheniramine and phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking chlorpheniramine and phenylpropanolamine.

Do not take more of this medication than is recommended. If your symptoms do not improve, or if they worsen, talk to your doctor.

Who should not take chlorpheniramine and phenylpropanolamine?

Do not take chlorpheniramine and phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• kidney disease,


• liver disease,


• 
  

  diabetes,

  
  


• 
  

  glaucoma,

  
  


• 
  

  any type of heart disease or high blood pressure,

  
  


• 
  

  thyroid disease,

  
  


• 
  

  emphysema or chronic bronchitis, or

  
  


• 
  

  difficulty urinating or an enlarged prostate.

  
  

You may not be able to take chlorpheniramine and phenylpropanolamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Chlorpheniramine and phenylpropanolamine is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. This medication passes into breast milk and may harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from chlorpheniramine and phenylpropanolamine. You may require a lower dose of this medication. Read the package label for directions or consult your doctor or pharmacist before treating a child with this medication. Children are more susceptible than adults to the effects of medicines and may have unusual reactions.

How should I take chlorpheniramine and phenylpropanolamine?

Take chlorpheniramine and phenylpropanolamine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Do not crush, chew, or break the long-acting or sustained-release forms of this medication. Swallow them whole. If you are unsure of the formulation of your medicine, ask your pharmacist for help.

If you cannot swallow the tablets or capsules, look for a liquid form of the medication.

To ensure that you get a correct dose, measure the liquid forms of chlorpheniramine and phenylpropanolamine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Do not take more of this medication than is recommended. An overdose of this medication can cause serious harm.

Do not take chlorpheniramine and phenylpropanolamine for longer than 7 days in a row. If your symptoms do not improve, if they get worse, or if you have a fever, talk to your doctor.

Store chlorpheniramine and phenylpropanolamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a chlorpheniramine and phenylpropanolamine overdose include a dry mouth, large pupils, flushing, nausea, and vomiting.

What should I avoid while taking chlorpheniramine and phenylpropanolamine?

Use caution when driving, operating machinery, or performing other hazardous activities. Chlorpheniramine and phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking chlorpheniramine and phenylpropanolamine.

Chlorpheniramine and phenylpropanolamine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if chlorpheniramine and phenylpropanolamine is taken with any of these medications.

Chlorpheniramine and phenylpropanolamine side effects

Serious side effects are unlikely to occur. Stop taking chlorpheniramine and phenylpropanolamine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take chlorpheniramine and phenylpropanolamine and talk to your doctor or try another similar medication if you experience

• 
  

  dryness of the eyes, nose, and mouth;

  
  


• 
  

  drowsiness or dizziness;

  
  


• 
  

  blurred vision;

  
  


• 
  

  difficulty urinating; or

  
  


• 
  

  excitation in children.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect chlorpheniramine and phenylpropanolamine?

Do not take chlorpheniramine and phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking chlorpheniramine and phenylpropanolamine without first talking to your doctor or pharmacist. Other medications may also contain chlorpheniramine, phenylpropanolamine, or other similar drugs. You may accidentally take too much of these medicines.

Chlorpheniramine and phenylpropanolamine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if chlorpheniramine and phenylpropanolamine is taken with any of these medications.

Drugs other than those listed here may also interact with chlorpheniramine and phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More Triaminic resources

• Triaminic Side Effects (in more detail)
• Triaminic Drug Interactions
• Triaminic Support Group
• 0 Reviews for Triaminic - Add your own review/rating

• Triaminic Consumer Overview

Compare Triaminic with other medications

• Cold Symptoms
• Cough and Nasal Congestion
• Hay Fever
• Sinusitis
• Upper Respiratory Tract Infection

Where can I get more information?

• Your pharmacist has additional information about chlorpheniramine and phenylpropanolamine written for health professionals that you may read.

What does my medication look like?

Many formulations of chlorpheniramine and phenylpropanolamine are available both over-the-counter and with a prescription. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

See also: Triaminic side effects (in more detail)

Novahistine Expectorant

Generic Name: codeine, guaifenesin, and pseudoephedrine (KOE deen, gwye FEN e sin, and soo doe e FED rin)

Brand Names: Ambifed CD, Ambifed CDX, Ambifed-G CD, Ambifed-G CDX, Biotussin DAC, Cheratussin DAC, Codafed, Codahistine Expectorant, Halotussin DAC, Maxifed CD, Medent C, Phenhist Expectorant

What is Novahistine Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Codeine is a narcotic cough suppressant.

Guaifenesin is an expectorant. It helps loosen mucus congestion in your chest and throat, making it easier to cough out through your mouth.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

The combination of codeine, guaifenesin, and pseudoephedrine is used to treat stuffy nose and cough, and to reduce chest congestion caused by the common cold, infections, or allergies.

Codeine, guaifenesin, and pseudoephedrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Novahistine Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains guaifenesin or pseudoephedrine. Codeine may be habit-forming and should be used only by the person it was prescribed for. Codeine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

What should I discuss with my healthcare provider before taking Novahistine Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. You should not take codeine, guaifenesin, and pseudoephedrine if you have ever had an allergic reaction to it, or if you have:

• 
  

  severe or uncontrolled high blood pressure;

  
  


• 
  

  severe coronary artery disease; or

  
  


• 
  

  if you are breast-feeding a baby.

  
  

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before taking codeine, guaifenesin, and pseudoephedrine, tell your doctor if you are allergic to any drugs, or if you have:

• 
  

  heart disease or high blood pressure;

  
  


• 
  

  ischemic heart disease (reduced circulation of blood to the heart);

  
  


• 
  

  asthma, COPD, sleep apnea, or other breathing disorders;

  
  


• 
  

  diabetes;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  glaucoma;

  
  


• liver or kidney disease;


• 
  

  a history of head injury or brain tumor;

  
  


• 
  

  epilepsy or other seizure disorder;

  
  


• 
  

  enlarged prostate, urination problems;

  
  


• 
  

  a stomach or intestinal disorder;

  
  


• 
  

  Addison's disease or other adrenal gland disorders;

  
  


• 
  

  if you have recently had surgery on your stomach, intestines, kidney, or bladder.

  
  


• 
  

  gallbladder disease;

  
  


• 
  

  mental illness; or

  
  


• 
  

  a history of drug or alcohol addiction.

  
  

If you have any of these conditions, you may not be able to use this medication, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Codeine can cause addiction or withdrawal symptoms in a newborn. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Codeine can pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication if you are breast-feeding a baby. Codeine may be habit-forming and should be used only by the person it was prescribed for. This medication should never be shared with another person, especially someone who has a history of drug abuse or addiction. Older adults may be more likely to have side effects from this medication.

How should I take Novahistine Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Take this medication exactly as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

Take codeine, guaifenesin, and pseudoephedrine with food if it upsets your stomach. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if your cough does not improve after 5 days of treatment, or if you also have a fever.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store this medicine at room temperature, away from heat, light, and moisture.

Keep track of how much of this medication has been used. Codeine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of codeine can be fatal.

Overdose symptoms may include nausea, vomiting, feeling restless or nervous, extreme dizziness or drowsiness, confusion, cold and clammy skin, shallow breathing, slow heart rate, pinpoint pupils, fainting, or coma.

What should I avoid while taking Novahistine Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Do not drink alcohol while you are taking this medication. Alcohol can increase some of the side effects of codeine. Do not use any other over-the-counter cold, allergy, or cough medicine without first asking your doctor or pharmacist. Guaifenesin and pseudoephedrine are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains guaifenesin or pseudoephedrine. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). This medication can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Novahistine Expectorant (codeine, guaifenesin, and pseudoephedrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  fast, pounding, or uneven heartbeat;

  
  


• 
  

  slow heart rate, weak pulse, fainting, weak or shallow breathing;

  
  


• 
  

  severe dizziness, anxiety, restless feeling, or nervousness, headache, tremors;

  
  


• 
  

  confusion, unusual thoughts or behavior;

  
  


• 
  

  seizure (convulsions);

  
  


• 
  

  urinating less than usual or not at all; or

  
  


• 
  

  increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).

  
  

Less serious side effects include:

• 
  

  dizziness or headache;

  
  


• 
  

  constipation;

  
  


• 
  

  nausea, vomiting, upset stomach, loss of appetite;

  
  


• 
  

  feeling excited or restless;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  increased sweating;

  
  


• 
  

  warmth, tingling, or redness under your skin; or

  
  


• 
  

  mild skin rash or itching.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Novahistine Expectorant (codeine, guaifenesin, and pseudoephedrine)?

Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by codeine or guaifenesin.

Also tell your doctor if you are using any of the following drugs:

• 
  

  medicines to treat high blood pressure;

  
  


• 
  

  indomethacin (Indocin);

  
  


• 
  

  methyldopa (Aldomet); or

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin), metoprolol (Lopressor, Toprol), propranolol (Inderal), sotalol (Betapace), and others.

  
  

This list is not complete and there may be other drugs that can interact with codeine, guaifenesin, and pseudoephedrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Novahistine Expectorant resources

• Novahistine Expectorant Side Effects (in more detail)
• Novahistine Expectorant Use in Pregnancy & Breastfeeding
• Novahistine Expectorant Drug Interactions
• Novahistine Expectorant Support Group
• 0 Reviews for Novahistine Expectorant - Add your own review/rating

• Ambifed CD MedFacts Consumer Leaflet (Wolters Kluwer)


• Mytussin DAC Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Novahistine Expectorant with other medications

• Cold Symptoms

Where can I get more information?

• Your pharmacist can provide more information about codeine, guaifenesin, and pseudoephedrine.

See also: Novahistine Expectorant side effects (in more detail)

sodium bicarbonate

Generic Name: sodium bicarbonate (sew dee uhm buy car bo nayt)

Brand names: Neut

What is sodium bicarbonate?

Sodium bicarbonate is an antacid that neutralizes stomach acid.

Sodium bicarbonate is used to relieve heartburn and indigestion. Sodium bicarbonate is also used to make the blood and urine less acidic in certain conditions

Sodium bicarbonate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about sodium bicarbonate?

Do not take sodium bicarbonate or any antacids without first talking to your doctor if you take any other medications.

Sodium bicarbonate contains a large amount of sodium. If you are on a sodium restricted diet or have high blood pressure talk to your health care professional before taking sodium bicarbonate.

What should I discuss with my healthcare provider before taking sodium bicarbonate?

Do not take sodium bicarbonate or any antacids without first talking to your doctor if you have:

• 
  

  an intestinal problem or appendicitis;

  
  


• 
  

  heart problems;

  
  


• 
  

  high blood pressure;

  
  


• 
  

  swelling of the arms or legs;

  
  


• 
  

  kidney disease;

  
  


• 
  

  liver disease; or

  
  


• 
  

  problems urinating;

  
  

Talk to your doctor before taking sodium bicarbonate if you are pregnant. Talk to your doctor before taking sodium bicarbonate if you are breast-feeding.

How should I take sodium bicarbonate?

Take sodium bicarbonate exactly as directed by your doctor or follow the directions on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take the sodium bicarbonate tablets with a full glass of water. Store sodium bicarbonate at room temperature away from moisture and heat.

See also: Sodium bicarbonate dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medicine unless your doctor directs otherwise.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

What should I avoid while taking sodium bicarbonate?

If you take other medicines, do not take sodium bicarbonate without first talking to your doctor.

Sodium bicarbonate side effects

Stop taking sodium bicarbonate and seek emergency medical attention if you experience a rare allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Stop taking sodium bicarbonate and notify your doctor if you experience

• 
  

  nausea or vomiting;

  
  


• 
  

  headache;

  
  


• 
  

  sever mood changes;

  
  


• 
  

  muscle pain;

  
  


• 
  

  swelling of feet, ankles or legs

  
  


• 
  

  decreased appetite;

  
  


• 
  

  unusual tiredness;

  
  


• 
  

  constipation;

  
  


• 
  

  dry mouth or increased thirst; or

  
  


• 
  

  increased urination.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Sodium bicarbonate Dosing Information

Usual Adult Dose for Metabolic Acidosis:

Parenteral:
If acid-base status is available, dosages should be calculated as follows: 0.2 x weight (kg) x base deficit.

Alternatively:

HCO3 (mEq) required = 0.5 x weight (kg) x [24 - serum HCO3 (mEq/L)].

or

Moderate metabolic acidosis: 50 to 150 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour during the first hour.

Severe metabolic acidosis: 90 to 180 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour during the first hour.

If acid-base status is not available, dosages should be calculated as follows: 2 to 5 mEq/kg IV infusion over 4 to 8 hours; subsequent doses should be based on patient's acid-base status.

Oral:

Moderate metabolic acidosis: 325 to 2000 mg orally 1 to 4 times a day. One gram provides 11.9 mEq (mmoL) each of sodium and bicarbonate.

Usual Adult Dose for Diabetic Ketoacidosis:

Although sodium bicarbonate is approved for the treatment of metabolic acidosis, data have shown that the use of this drug may be harmful in certain clinical settings such as lactic acidosis, acidosis with tissue hypoxia, uremia, severe cardiac dysfunction or arrest, and diabetic ketoacidosis.

Most experts only allow for its use when tissue perfusion and ventilation are maximized and the arterial pH is 7.1 or lower.

If sodium bicarbonate is used to treat diabetic ketoacidosis, the initial dosage is 50 mEq sodium bicarbonate in 1 L of appropriate IV solution to be given once.

Insulin therapy may obviate the need for bicarbonate therapy since it will promote glucose utilization and decrease the production of ketoacids.

Usual Adult Dose for Urinary Alkalinization:

Parenteral:

50 to 150 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour.

Oral:

325 to 2000 mg orally 1 to 4 times a day. One gram provides 11.9 mEq (mmoL) each of sodium and bicarbonate.

The goal of therapy is to correct serum pH and increase the urinary pH to 8 in order to increase the renal excretion of toxic substances such as salicylates or lithium.

If the increase in urinary pH is inadequate, increasing the sodium bicarbonate in solution to 100 to 150 mEq/L may result in further alkalinization of the urine.

Usual Adult Dose for Dyspepsia:

325 to 2000 mg orally 1 to 4 times a day.

Usual Adult Dose for Hyperkalemia:

One ampule of 7.5% sodium bicarbonate (44.6 mEq HCO3 ion) may be administered slowly IV over 5 minutes and repeated at 10 to 15 minute intervals if ECG changes persist. The onset of action occurs within 30 minutes and the effect lasts for 1 to 2 hours. The resultant effect restores intracellular potassium levels to normal without decreasing total body potassium stores.

Circulatory overload and hypernatremia can occur when large volumes of hypertonic sodium bicarbonate are given. If hypocalcemia is present, seizures and tetany may occur as blood pH rises and the ionized free calcium decreases; hence, calcium should be given first. Hyponatremia will magnify the cardiac effects of hyperkalemia, and sodium bicarbonate can be used to treat this as well.

Usual Adult Dose for Asystole:

1 mEq/kg slow IV initially, may repeat with 0.5 mEq/kg 10 minutes later one time, or as indicated by the patient's acid-base status.

Usual Pediatric Dose for Metabolic Acidosis:

If acid-base status is available, dosages should be calculated as follows:
Infants and Children: HCO3 (mEq) required = 0.3 x weight (kg) x base deficit (mEq/L) OR HCO3 (mEq) required = 0.5 x weight (kg) x [24 - serum HCO3 (mEq/L)].

If acid-base status is not available, dosages should be calculated as follows:
Older children: 2 to 5 mEq/kg IV infusion over 4 to 8 hours; subsequent doses should be based on patient acid-base status.

Usual Pediatric Dose for Urinary Alkalinization:

0 to 12 years: 1 to 10 mEq (84 to 840 mg)/kg/day orally in divided doses; dose should be titrated to desired urinary pH.

Greater than 12 to 18 years: 325 to 2000 mg orally 1 to 4 times a day. One gram provides 11.9 mEq (mmol) each of sodium and bicarbonate.

The goal of therapy is to correct serum pH and increase the urinary pH to 8 in order to increase the renal excretion of toxic substances such as salicylates or lithium.

If the increase in urinary pH is inadequate, increasing the sodium bicarbonate in solution to 100 to 150 mEq/L may result in further alkalinization of the urine.

Usual Pediatric Dose for Hyperuricemia Secondary to Chemotherapy:

0 to 12 years:

Parenteral:
120 to 200 mEq/m2/day diluted in maintenance IV fluids of 3000 mL/m2/day; titrate to maintain urine pH between 6 and 7.

Oral:
12 g/m2/day divided into 4 doses; titrate to maintain urine pH between 6 and 7.

Usual Pediatric Dose for Asystole:

1 mEq/kg slow IV initially, may repeat with 0.5 mEq/kg 10 minutes later one time, or as indicated by the patient acid-base status.

What other drugs will affect sodium bicarbonate?

Before taking sodium bicarbonate, tell your doctor if you are taking

• 
  

  mecamylamine (Inversine);

  
  


• 
  

  methenamine (Mandelamine);

  
  


• 
  

  ketoconazole (Nizoral);

  
  


• 
  

  antacids;

  
  


• 
  

  a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others).

  
  

You may not be able to take sodium bicarbonate, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with sodium bicarbonate. Talk to your doctor or pharmacist before taking any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

More sodium bicarbonate resources

• Sodium bicarbonate Side Effects (in more detail)
• Sodium bicarbonate Dosage
• Sodium bicarbonate Use in Pregnancy & Breastfeeding
• Drug Images
• Sodium bicarbonate Drug Interactions
• Sodium bicarbonate Support Group
• 0 Reviews for Sodium bicarbonate - Add your own review/rating

• sodium bicarbonate Oral, Intravenous, Subcutaneous Advanced Consumer (Micromedex) - Includes Dosage Information


• Sodium Bicarbonate Prescribing Information (FDA)


• Sodium Bicarbonate Professional Patient Advice (Wolters Kluwer)


• Sodium Bicarbonate Monograph (AHFS DI)


• Sodium Bicarbonate MedFacts Consumer Leaflet (Wolters Kluwer)

Compare sodium bicarbonate with other medications

• Asystole
• Diabetic Ketoacidosis
• Hyperkalemia
• Hyperuricemia Secondary to Chemotherapy
• Indigestion
• Metabolic Acidosis
• Urinary Alkalinization

Where can I get more information?

• Your doctor, pharmacist, or health care provider may have more information about sodium bicarbonate.

See also: sodium bicarbonate side effects (in more detail)

chondroitin, glucosamine, and methylsulfonylmethane

Generic Name: chondroitin, glucosamine, and methylsulfonylmethane (kon DROI tin, gloo KOSE a meen, and METH il sul FON il METH ane)

Brand names: Glucosamine & Chondroitin with MSM, Glucosamine Chondroitin MSM Complex, Osteo Bi-Flex Advanced, Osteo Bi-Flex Plus MSM, Glucosamine & Chondroitin with MSM

What is chondroitin, glucosamine, and methylsulfonylmethane?

Chondroitin is a naturally occurring substance formed of sugar chains. Chondroitin is believed to help the body maintain fluid and flexibility in the joints.

Glucosamine is a naturally occurring substance that is believed to help develop and renew cartilage (the hard connective tissue mainly located on bones near joints in the body), and keep it lubricated for better joint movement and flexibility.

Methylsulfonylmethane is a naturally occurring form of sulfur that helps support muscles and tendons in the body.

The combination of chondroitin, glucosamine, and methylsulfonylmethane is used to aid in maintaining healthy joints. It is also used as a nutritional supplement in people with osteoarthritis or other inflammatory joint disorders.

Not all uses for chondroitin, glucosamine, and methylsulfonylmethane have been approved by the FDA. Chondroitin, glucosamine, and methylsulfonylmethane should not be used in place of medication prescribed for you by your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Chondroitin, glucosamine, and methylsulfonylmethane may also be used for purposes not listed in this product guide.

What is the most important information I should know about chondroitin, glucosamine, and methylsulfonylmethane?

Not all uses for this product have been approved by the FDA. Chondroitin, glucosamine, and methylsulfonylmethane should not be used in place of medication prescribed for you by your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Before using this product, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use chondroitin, glucosamine, and methylsulfonylmethane if you have diabetes, a bleeding or blood clotting disorder such as hemophilia, if you have allergies to certain drugs, if you are overweight, or if you are on a low-salt diet.

Do not take chondroitin, glucosamine, and methylsulfonylmethane without the medical advice if you are using insulin, or a blood thinner such as warfarin (Coumadin, Jantoven). Avoid taking chitosan (usually marketed as a weight-loss product) while you are taking chondroitin, glucosamine, and methylsulfonylmethane. Chitosan can make it harder for your body to absorb chondroitin.

What should I discuss with my healthcare provider before taking chondroitin, glucosamine, and methylsulfonylmethane?

You should not use this product if you are allergic to it.

Ask a doctor, pharmacist, herbalist, or other healthcare provider if it is safe for you to use this product if you have:

• 
  

  diabetes;

  
  


• 
  

  a bleeding or blood clotting disorder such as hemophilia;

  
  


• 
  

  if you have allergies to certain drugs;

  
  


• 
  

  if you are overweight; or

  
  


• 
  

  if you are on a low-salt diet.

  
  

It is not known whether chondroitin, glucosamine, and methylsulfonylmethane will harm an unborn baby. Tell your healthcare provider if you are pregnant or plan to become pregnant while using this product. It is not known whether chondroitin, glucosamine, and methylsulfonylmethane passes into breast milk or if it could harm a nursing baby. Do not use this product without telling your healthcare provider if you are breast-feeding a baby.

How should I take chondroitin, glucosamine, and methylsulfonylmethane?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use chondroitin, glucosamine, and methylsulfonylmethane, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

It may take up several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after a few weeks of treatment.

Glucosamine may increase the glucose (sugar) levels in your blood. If you have diabetes, you may need to check your blood sugar more often while taking this medication. You may also need to adjust your insulin dosage. Do not change your dose or medication schedule without advice from your doctor.

Chondroitin, glucosamine, and methylsulfonylmethane may be only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking chondroitin, glucosamine, and methylsulfonylmethane?

Avoid taking chitosan (usually marketed as a weight-loss product) while you are taking chondroitin, glucosamine, and methylsulfonylmethane. Chitosan can make it harder for your body to absorb chondroitin.

Chondroitin, glucosamine, and methylsulfonylmethane side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

• 
  

  mild nausea, upset stomach;

  
  


• 
  

  heartburn; or

  
  


• 
  

  diarrhea.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect chondroitin, glucosamine, and methylsulfonylmethane?

Tell your doctor about all other medicines you use, especially:

• 
  

  insulin; or

  
  


• 
  

  a blood thinner such as warfarin (Coumadin, Jantoven).

  
  

This list is not complete and other drugs may interact with chondroitin, glucosamine, and methylsulfonylmethane. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More chondroitin, glucosamine, and methylsulfonylmethane resources

• Chondroitin, glucosamine, and methylsulfonylmethane Drug Interactions
• Chondroitin, glucosamine, and methylsulfonylmethane Support Group
• 1 Review for Chondroitin, glucosamine, and methylsulfonylmethane - Add your own review/rating

Compare chondroitin, glucosamine, and methylsulfonylmethane with other medications

• Dietary Supplementation
• Osteoarthritis

Where can I get more information?

• Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

Urocit-K 10 Oral, Parenteral

Generic Name: potassium supplement (Oral route, Parenteral route)

Commonly used brand name(s)

In the U.S.

• Effer-K


• Glu-K


• K+Care ET


• K-Lyte


• K-Lyte Cl


• K-Tab


• Potassimin


• Tri-K


• Urocit-K 10

In Canada

• K-10 Solution


• Kaochlor 10


• Kaochlor 20


• Kaon


• K-Lor


• K-Lyte/Ci


• Potassium Chloride


• Potassium-Rougier


• Roychlor

Available Dosage Forms:

• Tablet, Effervescent


• Solution


• Capsule


• Tablet, Extended Release


• Powder for Suspension, Extended Release


• Tablet


• Powder for Suspension


• Liquid


• Elixir


• Granule


• Capsule, Extended Release


• Powder for Solution

Uses For Urocit-K 10

Potassium is needed to maintain good health. Although a balanced diet usually supplies all the potassium a person needs, potassium supplements may be needed by patients who do not have enough potassium in their regular diet or have lost too much potassium because of illness or treatment with certain medicines.

There is no evidence that potassium supplements are useful in the treatment of high blood pressure.

Lack of potassium may cause muscle weakness, irregular heartbeat, mood changes, or nausea and vomiting.

Injectable potassium is administered only by or under the supervision of your doctor. Some forms of oral potassium may be available in stores without a prescription. Since too much potassium may cause health problems, you should take potassium supplements only if directed by your doctor.

Importance of Diet

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods.

The following table includes some potassium-rich foods.

Food (amount)	Milligrams of potassium	Milliequivalents of potassium
Acorn squash, cooked (1 cup)	896	23
Potato with skin, baked (1 long)	844	22
Spinach, cooked (1 cup)	838	21
Lentils, cooked (1 cup)	731	19
Kidney beans, cooked (1 cup)	713	18
Split peas, cooked (1 cup)	710	18
White navy beans, cooked (1 cup)	669	17
Butternut squash, cooked (1 cup)	583	15
Watermelon (1/16)	560	14
Raisins (½ cup)	553	14
Yogurt, low-fat, plain (1 cup)	531	14
Orange juice, frozen (1 cup)	503	13
Brussel sprouts, cooked (1 cup)	494	13
Zucchini, cooked, sliced (1 cup)	456	12
Banana (medium)	451	12
Collards, frozen, cooked (1 cup)	427	11
Cantaloupe (¼)	412	11
Milk, low-fat 1% (1 cup)	348	9
Broccoli, frozen, cooked (1 cup)	332	9

The daily amount of potassium needed is defined in several different ways.

• For U.S.—


• Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person's age, sex, and physical condition (e.g., pregnancy).


• Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).

• For Canada—


• Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

Because lack of potassium is rare, there is no RDA or RNI for this mineral. However, it is thought that 1600 to 2000 mg (40 to 50 milliequivalents [mEq]) per day for adults is adequate.

Remember:

• The total amount of potassium that you get every day includes what you get from food and what you may take as a supplement. Read the labels of processed foods. Many foods now have added potassium.


• Your total intake of potassium should not be greater than the recommended amounts, unless ordered by your doctor. In some cases, too much potassium may cause muscle weakness, confusion, irregular heartbeat, or difficult breathing.

Before Using Urocit-K 10

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of potassium supplements in children with use in other age groups, they are not expected to cause different side effects or problems in children than they do in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of potassium supplements in the elderly with use in other age groups, they are not expected to cause different side effects or problems in older people than they do in younger adults.

Older adults may be at a greater risk of developing high blood levels of potassium (hyperkalemia).

Pregnancy

Potassium supplements have not been shown to cause problems in humans.

Breast Feeding

Potassium supplements pass into breast milk. However, this medicine has not been reported to cause problems in nursing babies.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these dietary supplements, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using dietary supplements in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with dietary supplements in this class or change some of the other medicines you take.

• Amantadine


• Atropine


• Belladonna


• Belladonna Alkaloids


• Benztropine


• Biperiden


• Clidinium


• Darifenacin


• Dicyclomine


• Eplerenone


• Glycopyrrolate


• Hyoscyamine


• Methscopolamine


• Oxybutynin


• Procyclidine


• Scopolamine


• Solifenacin


• Tolterodine


• Trihexyphenidyl

Using dietary supplements in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alacepril


• Amiloride


• Benazepril


• Canrenoate


• Captopril


• Cilazapril


• Delapril


• Enalaprilat


• Enalapril Maleate


• Fosinopril


• Imidapril


• Indomethacin


• Lisinopril


• Moexipril


• Pentopril


• Perindopril


• Quinapril


• Ramipril


• Spirapril


• Spironolactone


• Temocapril


• Trandolapril


• Triamterene


• Zofenopril

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of dietary supplements in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Addison's disease (underactive adrenal glands) or


• Dehydration (excessive loss of body water, continuing or severe)


• Type 2 diabetes mellitus or


• Kidney disease—Potassium supplements may increase the risk of hyperkalemia (high blood levels of potassium), which may worsen or cause heart problems in patients with these conditions.

• Diarrhea (continuing or severe)—The loss of fluid in combination with potassium supplements may cause kidney problems, which may increase the risk of hyperkalemia (high blood levels of potassium).

• Heart disease—Potassium supplements may make this condition worse.

• Intestinal or esophageal blockage—Potassium supplements may damage the intestines.

• Stomach ulcer—Potassium supplements may make this condition worse.

Proper Use of potassium supplement

This section provides information on the proper use of a number of products that contain potassium supplement. It may not be specific to Urocit-K 10. Please read with care.

For patients taking the liquid form of this medicine:

• This medicine must be diluted in at least one-half glass (4 ounces) of cold water or juice to reduce its possible stomach-irritating or laxative effect.


• If you are on a salt (sodium)-restricted diet, check with your doctor before using tomato juice to dilute your medicine. Tomato juice has a high salt content.

For patients taking the soluble granule, soluble powder, or soluble tablet form of this medicine:

• This medicine must be completely dissolved in at least one-half glass (4 ounces) of cold water or juice to reduce its possible stomach-irritating or laxative effect.


• Allow any "fizzing" to stop before taking the dissolved medicine.


• If you are on a salt (sodium)-restricted diet, check with your doctor before using tomato juice to dilute your medicine. Tomato juice has a high salt content.

For patients taking the extended-release tablet form of this medicine:

• Swallow the tablets whole with a full (8-ounce) glass of water. Do not chew or suck on the tablet.


• Some tablets may be broken or crushed and sprinkled on applesauce or other soft food. However, check with your doctor or pharmacist first, since this should not be done for most tablets.


• If you have trouble swallowing tablets or if they seem to stick in your throat, check with your doctor. When this medicine is not properly released, it can cause irritation that may lead to ulcers.

For patients taking the extended-release capsule form of this medicine:

• Do not crush or chew the capsule. Swallow the capsule whole with a full (8-ounce) glass of water.


• Some capsules may be opened and the contents sprinkled on applesauce or other soft food. However, check with your doctor or pharmacist first, since this should not be done for most capsules.

Take this medicine immediately after meals or with food to lessen possible stomach upset or laxative action.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important if you are also taking both diuretics (water pills) and digitalis medicines for your heart.

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For potassium bicarbonate


• For oral dosage forms (tablets for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—25 to 50 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  

• For potassium bicarbonate and potassium chloride


• For oral dosage form (granules for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  


• For oral dosage form (tablets for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20, 25, or 50 mEq dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  

• For potassium bicarbonate and potassium citrate


• For oral dosage form (tablets for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—25 or 50 milliequivalents (mEq) dissolved in one-half to one glass of cold water, taken one or two times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  

• For potassium chloride


• For long-acting oral dosage form (extended-release capsules):
  
  • To replace potassium lost by the body:
    
    • Adults and teenagers—40 to 100 milliequivalents (mEq) a day, divided into two or three smaller doses during the day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
  
  
  • To prevent potassium loss:
    
    • Adults and teenagers—16 to 24 mEq a day, divided into two or three smaller doses during the day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  


• For long-acting oral dosage forms (liquid for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20 mEq mixed into one-half glass of cold water or juice, taken one to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 3 mEq of potassium per kilogram (kg) (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed in water or juice.
    
    
  
  


• For oral dosage form (powder for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—15 to 25 mEq dissolved in four to six ounces of cold water, taken two or four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 to 3 mEq per kg (0.45 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be mixed into water or juice.
    
    
  
  


• For oral dosage form (powder for suspension):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20 mEq dissolved in two to six ounces of cold water, taken one to five times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  


• For long-acting oral dosage form (extended-release tablets):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—6.7 to 20 mEq taken three times a day. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  


• For oral dosage form (liquid for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight a day, taken in smaller doses during the day. The solution should be completely mixed into water or juice.
    
    
  
  


• For oral dosage form (tablets):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—5 to 10 mEq taken two to four times a day. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose must be determined by your doctor.
    
    
  
  

• For potassium gluconate and potassium chloride


• For oral dosage form (liquid for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20 milliequivalents (mEq) diluted in 2 tablespoonfuls or more of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
    
    
  
  


• For oral dosage form (powder for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20 mEq mixed in 2 tablespoonfuls or more of cold water or juice taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose is base on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kg (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
    
    
  
  

• For potassium gluconate and potassium citrate


• For oral dosage form (liquid for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kg (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
    
    
  
  

• For trikates


• For oral dosage form (liquid for solution):
  
  • To prevent potassium loss or replace potassium lost by the body:
    
    • Adults and teenagers—15 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken three or four times a day. Your doctor may change the dose if needed. However, most people will not take more than 100 mEq a day.
    
    
    • Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 2 to 3 mEq per kilogram (kg) (0.9 to 1.36 mEq per pound) of body weight taken in smaller doses during the day. The solution should be well mixed into water or juice.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Urocit-K 10

Your doctor should check your progress at regular visits to make sure the medicine is working properly and that possible side effects are avoided. Laboratory tests may be necessary.

Do not use salt substitutes, eat low-sodium foods, especially some breads and canned foods, or drink low-sodium milk unless you are told to do so by your doctor, since these products may contain potassium. It is important to read the labels carefully on all low-sodium food products.

Check with your doctor before starting any physical exercise program, especially if you are out of condition and are taking any other medicine. Exercise and certain medicines may increase the amount of potassium in the blood.

Check with your doctor at once if you notice blackish stools or other signs of stomach or intestinal bleeding. This medicine may cause such a condition to become worse, especially when taken in tablet form.

Urocit-K 10 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking this medicine and check with your doctor immediately if any of the following side effects occur:

Less common

• Confusion


• irregular or slow heartbeat


• numbness or tingling in hands, feet, or lips


• shortness of breath or difficult breathing


• unexplained anxiety


• unusual tiredness or weakness


• weakness or heaviness of legs

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

• Abdominal or stomach pain, cramping, or soreness (continuing)


• chest or throat pain, especially when swallowing


• stools with signs of blood (red or black color)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Diarrhea


• nausea


• stomach pain, discomfort, or gas (mild)


• vomiting

Sometimes you may see what appears to be a whole tablet in the stool after taking certain extended-release potassium chloride tablets. This is to be expected. Your body has absorbed the potassium from the tablet and the shell is then expelled.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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